Pus10 Mouse shRNA Plasmid (Locus ID 74467)
Specifications
| Product Data | |
| Locus ID | 74467 |
|---|---|
| Synonyms | 2810013G11Rik; 4933435A13Rik; AU014648; C77560; Ccdc139 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Pus10 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 74467). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC025555, NM_001033654, NM_028304, NM_028956, NM_028304.1, NM_028304.2, NM_001033654.1, NM_001033654.2, NM_028956.4, NM_028304.3 |
| UniProt ID | Q9D3U0 |
| Summary | Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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