Mrgbp Mouse shRNA Plasmid (Locus ID 73247)
Specifications
| Product Data | |
| Locus ID | 73247 |
|---|---|
| Synonyms | 1600027N09Rik; AW060503; C80444 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Mrgbp - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 73247). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC110993, BC116732, BC116734, NM_028479, NM_001356494, NR_151481, NR_151482, NM_028479.1, BC042508, BC054431, BC085320, NM_028479.2 |
| UniProt ID | Q9DAT2 |
| Summary | Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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