Smg9 Mouse shRNA Plasmid (Locus ID 71997)
Specifications
| Product Data | |
| Locus ID | 71997 |
|---|---|
| Synonyms | 1500002O20Rik; AI429693; N28092 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Smg9 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 71997). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC034211, NM_028047, NM_028047.1, NM_028047.2 |
| UniProt ID | Q9DB90 |
| Summary | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (By similarity). Plays a role in brain, heart, and eye development (PubMed:27018474).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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