Pdia6 Mouse shRNA Plasmid (Locus ID 71853)
Specifications
| Product Data | |
| Locus ID | 71853 |
|---|---|
| Synonyms | 1700015E05Rik; AL023058; C77895; CaBP5; P5; Txndc7 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Pdia6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 71853). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC006865, NM_027959, NM_027959.1, NM_027959.2, NM_027959.3 |
| UniProt ID | Q922R8 |
| Summary | May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:24508390). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (By similarity). May also regulate the UPR via the EIF2AK3 UPR sensor (By similarity). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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