Ube2v2 Mouse shRNA Plasmid (Locus ID 70620)
Specifications
| Product Data | |
| Locus ID | 70620 |
|---|---|
| Synonyms | 1110021H13Rik; 4632410D19Rik; 5730524P06Rik; 6820402M05; AI848315; C81524; MMS2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ube2v2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 70620). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC058374, BC083098, BC094903, NM_001159351, NM_023585, NM_023585.1, NM_023585.2, NM_023585.3, NM_023585.4, NM_001159351.1, BC029742, BC044722 |
| UniProt ID | Q9D2M8 |
| Summary | Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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