Draxin Mouse shRNA Plasmid (Locus ID 70433)
Specifications
| Product Data | |
| Locus ID | 70433 |
|---|---|
| Synonyms | 2610109H07Rik; neucrin |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Draxin - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 70433). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC060239, NM_027426, NM_027426.1, NM_027426.2, NM_027426.3, BC057066, BC058734 |
| UniProt ID | Q6PAL1 |
| Summary | Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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