Tyw5 Mouse shRNA Plasmid (Locus ID 68736)
Specifications
| Product Data | |
| Locus ID | 68736 |
|---|---|
| Synonyms | 1110034B05Rik |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Tyw5 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 68736). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC132289, NM_001037742, NM_001114102, NM_001302962, NM_001302963, NM_001302964, NR_004860, NM_001037742.1, NM_001037742.2, NM_001114102.1, NM_001302963.1, NM_001302964.1, NM_001302962.1, BC023868, BC058590, BC099495, BC144765, BC144766 |
| UniProt ID | A2RSX7 |
| Summary | tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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