Tceb1 Mouse shRNA Plasmid (Locus ID 67923)
Specifications
| Product Data | |
| Locus ID | 67923 |
|---|---|
| Synonyms | 2610043E24Rik; 2610301I15Rik; AA407206; AI987979; AW049146; Tceb1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Eloc - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 67923). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC009104, BC028545, NM_001310470, NM_026456, NM_026456.1, NM_026456.2, NM_026456.3, NM_026456.4 |
| UniProt ID | P83940 |
| Summary | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (By similarity). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (PubMed:27863225, PubMed:27863226).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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