Shoc2 Mouse shRNA Plasmid (Locus ID 56392)
Specifications
| Product Data | |
| Locus ID | 56392 |
|---|---|
| Synonyms | AU017287; mKIAA0862; Sur8 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Shoc2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 56392). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC026364, BC049775, BC083060, NM_001168505, NM_019658, NM_001355242, NM_001168505.1, NM_019658.1, NM_019658.2, NM_019658.3, NM_019658.4, NM_019658.5, NM_019658.6, BC013722 |
| UniProt ID | O88520 |
| Summary | Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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