Astn2 Mouse shRNA Plasmid (Locus ID 56079)
Specifications
| Product Data | |
| Locus ID | 56079 |
|---|---|
| Synonyms | 1d8; Astnl; bM452J22.1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Astn2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 56079). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_019514, NM_207109, NM_019514.1, NM_019514.2, NM_019514.3, NM_207109.1, NM_207109.2 |
| UniProt ID | Q80Z10 |
| Summary | Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (PubMed:20573900). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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