Zbtb18 Mouse shRNA Plasmid (Locus ID 30928)
Specifications
| Product Data | |
| Locus ID | 30928 |
|---|---|
| Synonyms | RP58; zfp-238; Zfp238; Znf238 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Zbtb18 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 30928). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC054529, BC054742, NM_001012330, NM_013915, NM_001355098, NM_001355099, NM_001355100, NM_001355101, NM_001355102, NM_001355103, NM_013915.1, NM_013915.2, NM_013915.3, NM_001012330.1, BC050909, BC089333 |
| UniProt ID | Q9WUK6 |
| Summary | Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Specifically binds the consensus DNA sequence 5'-ACACATCTGGTAC-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. May also play a role in the organization of chromosomes in the nucleus.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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