Polr2m Mouse shRNA Plasmid (Locus ID 28015)
Specifications
| Product Data | |
| Locus ID | 28015 |
|---|---|
| Synonyms | AA407243; AA408799; AI303746; AW553238; D9Wsu138e; Grinl1a; mKIAA4185 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Polr2m - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 28015). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC018502, BC062199, NM_001164793, NM_178602, NM_001164793.1, NM_178602.1, NM_178602.2, NM_178602.3 |
| UniProt ID | Q6P6I6 |
| Summary | Isoform 1 appears to be stable component of the Pol II(G) complex form of RNA polymerase II. Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery. Isoform 1 may play a role in Mediator-dependent regulation of transcription activation. Isoform 1 acts in vitro as negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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