Klf10 Mouse shRNA Plasmid (Locus ID 21847)
Specifications
| Product Data | |
| Locus ID | 21847 |
|---|---|
| Synonyms | AI115143; Egral; EGRa; Gdnfif; mGIF; Tieg; TIEG-1; Tieg1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Klf10 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 21847). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC003316, NM_001289471, NM_013692, NM_001357677, NM_013692.1, NM_013692.2, NM_013692.3, NM_001289471.1 |
| UniProt ID | O89091 |
| Summary | Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. May play a role in the cell cycle regulation (By similarity). Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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