Tfap2b Mouse shRNA Plasmid (Locus ID 21419)
Specifications
| Product Data | |
| Locus ID | 21419 |
|---|---|
| Synonyms | AI606113; AP-2(beta); E130018K07Rik; Tcfap2b |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Tfap2b - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector (Gene ID = 21419). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001025305, NM_001286340, NM_009334, NM_009334.1, NM_009334.2, NM_009334.3, NM_001025305.1, NM_001025305.2, NM_001286340.1, BC146412, BC148852 |
| UniProt ID | Q61313 |
| Summary | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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