Ralbp1 Mouse shRNA Plasmid (Locus ID 19765)
Specifications
| Product Data | |
| Locus ID | 19765 |
|---|---|
| Synonyms | Rip1; RLIP76 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ralbp1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 19765). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC067073, BC075732, BC076636, NM_001198949, NM_009067, NM_009067.1, NM_009067.2, NM_009067.3, NM_009067.4, NM_009067.5, NM_001198949.1, BC028516, BC054329, BC138546, BC145320, BC145815 |
| UniProt ID | Q62172 |
| Summary | Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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