Ptpre Mouse shRNA Plasmid (Locus ID 19267)
Specifications
| Product Data | |
| Locus ID | 19267 |
|---|---|
| Synonyms | PTPe; PTPepsilon; RPTPepsilon |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ptpre - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 19267). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001316678, NM_001316679, NM_001316680, NM_001316681, NM_011212, NM_011212.1, NM_011212.2, NM_011212.3, BC024631, BC053408, BC098473, BC160345 |
| UniProt ID | P49446 |
| Summary | Isoform 1 acts as a negative regulator of insulin receptor (IR) signaling and is involved in insulin-induced glucose metabolism mainly through direct dephosphorylation and inactivation of IR in hepatocytes and liver (By similarity). Plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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