Pax6 Mouse shRNA Plasmid (Locus ID 18508)
Specifications
| Product Data | |
| Locus ID | 18508 |
|---|---|
| Synonyms | 1500038E17Rik; AEY1; AEY11; Dey; Gsfaey; Gsfaey11; Pax; Pax-6; Sey |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Pax6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 18508). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC011272, BC036957, NM_001244198, NM_001244200, NM_001244201, NM_001244202, NM_013627, NM_013627.1, NM_013627.2, NM_013627.3, NM_013627.4, NM_013627.5, NM_013627.6, NM_001244201.1, NM_001244201.2, NM_001244202.1, NM_001244202.2, NM_001244198.1, NM_001244198.2, NM_001244200.1, NM_001244200.2, BC069912 |
| UniProt ID | P63015 |
| Summary | This gene encodes a homeobox-containing protein that functions as a regulator of transcription. It plays a key role in the development of neural tissues, particularly the eye. Activity of this protein is also required for expression of glucagon in the pancreas. This gene is regulated by multiple enhancers located up to tens or hundreds of kilobases upstream and downstream of the transcription start sites. Mutations in this gene or deletion of these regulatory elements results in severe defects in eye development. Alternative splicing and the use of alternative promoters results in multiple transcript variants, some of which encode proteins that lack the N-terminal paired domain. provided by RefSeq, Jul 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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