Mbd3 Mouse shRNA Plasmid (Locus ID 17192)
Specifications
| Product Data | |
| Locus ID | 17192 |
|---|---|
| Synonyms | AI181826; AU019209 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Mbd3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 17192). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC038264, NM_013595, NM_013595.1, NM_013595.2, NM_013595.3 |
| UniProt ID | Q9Z2D8 |
| Summary | This gene encodes a member of the MBD family of nuclear proteins that contain a methyl-CpG binding domain (MBD). The encoded protein is a component of the nucleosome remodeling and histone deacetylation (NuRD) complex. Deletion of this gene causes embryonic lethality in mice. Embryonic stem cells lacking the encoded protein are severely compromised in their ability to differentiate and fail to commit to developmental lineages in the absence of leukemia inhibitory factor. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Apr 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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