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Jup Mouse shRNA Plasmid (Locus ID 16480)

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SKU
TR501141
Jup - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 16480
Synonyms Ctnng; D930025P04Rik; PG
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Jup - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 16480). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC040757, BC094461, NM_010593, NM_010593.1, NM_010593.2
UniProt ID Q02257
Summary Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation
Mahendram, Kelly, Paez-Parent et al
PLoS ONE (2013) 8 (5), e65320 DOI: 10.1371/journal.pone.0065320
Cited by 20
AI Summary: OriGene’s HuSH 29mer shRNA constructs against Jup (Cat. No. TG502227) were used in this study to knock down γ-catenin expression, enabling the authors to investigate its role in Wnt signaling and embryonic stem cell differentiation.
Snippet: Materials and Methods. Cell culture. Cell culture supplements were obtained from Gibco (Life Technologies) unless otherwise specified. ... shRNA-mediated knockdown of γ-catenin expression. HuSH 29mer shRNA constructs against Jup were purchased from Origene (Cat. No.
FigureFigureFigure
Showing 1-1 of 1 papers.
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