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Jund Mouse shRNA Plasmid (Locus ID 16478)

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SKU
TR501140
Jund - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 16478
Synonyms Jund1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Jund - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 16478). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC010572, BC094068, NM_001286944, NM_010592, NM_010592.1, NM_010592.2, NM_010592.3, NM_010592.4, NM_010592.5, NM_001286944.1, BC023211
UniProt ID P15066
Summary The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). provided by RefSeq, Nov 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Human T-cell leukemia virus type 1 (HTLV-1) bZIP factor requires cellular transcription factor JunD to upregulate HTLV-1 antisense transcription from the 3' long terminal repeat
Gazon, Lemasson, Polakowski et al
J Virol (2012) 86 (17), 9070-8 DOI: 10.1128/JVI.00661-12
AI Summary: OriGene products contributed to this study by providing the JunD shRNA (OriGene, Cat# TL313803) used for knockdown experiments to assess the role of JunD in HBZ-mediated upregulation of HTLV-1 antisense transcription.
Overexpression of transcription factor Sp1 leads to gene expression perturbations and cell cycle inhibition
Deniaud, Baguet, Chalard et al
PLoS ONE (2009) 4 (9), e7035 DOI: 10.1371/journal.pone.0007035
Cited by 103
AI Summary: OriGene products pGFP-V-RS shRNA against hJunD (TG312046) and p-RS shRNA against mJunD (TR501140) were used in this study to manipulate JunD expression, enabling the investigation of gene expression changes and cell cycle effects resulting from Sp1 overexpression.
Snippet: In some cells, Tax expression is eliminated by deletion or methylation of the promoter located in the 5′ long terminal repeat (LTR ... pGFP-V-RS shRNA against hJunD (TG312046) and p-RS shRNA against mJunD (TR501140) were purchased from Origene, and pCR3-SP1 and
Showing 1-2 of 2 papers.
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