Itm2b Mouse shRNA Plasmid (Locus ID 16432)
Specifications
| Product Data | |
| Locus ID | 16432 |
|---|---|
| Synonyms | AI256040; Bri; Bri2; Bricd2b; D14Sel6; E25BMM; imBRI2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Itm2b - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 16432). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC004731, BC010320, BC021786, NM_008410, NM_008410.1, NM_008410.2 |
| UniProt ID | O89051 |
| Summary | Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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