Il6ra Mouse shRNA Plasmid (Locus ID 16194)
SKU
TR501088
Il6ra - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 16194 |
|---|---|
| Synonyms | CD126; IL-6R; IL-6R-alpha; IL-6RA; Il6r |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Il6ra - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 16194). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001310676, NM_010559, NM_010559.1, NM_010559.2, NM_010559.3, BC019388, BC038306, BC148583 |
| UniProt ID | P22272 |
| Summary | Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages
Liao, Lin, Wang et al
Nat. Immunol. (2011) 12 (6), 551-9 DOI: 10.1038/ni.2030
Liao, Lin, Wang et al
Nat. Immunol. (2011) 12 (6), 551-9 DOI: 10.1038/ni.2030
Cited by 473
AI Summary: OriGene contributed plasmids pRV-mIl6ra and pRV-mIl6st, which were used for retroviral transduction to study the role of IL-6 receptor components in helper T cell differentiation.
Showing 1-1 of 1 papers.
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