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Irf8 Mouse shRNA Plasmid (Locus ID 15900)

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SKU
TR501032
Irf8 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 15900
Synonyms AI893568; IC; Ics; ICSBP; Icsbp1; IRF; IRF-8; My; Myls
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Irf8 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 15900). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC005450, NM_001301811, NM_008320, NM_008320.1, NM_008320.2, NM_008320.3, NM_008320.4, NM_001301811.1
UniProt ID P23611
Summary The protein encoded by this gene is a transcription factor that belongs to the interferon regulatory factor family. Proteins belonging to this family have a DNA binding domain at the amino terminus that contains five well-conserved tryptophan-rich repeats. This domain recognizes DNA sequences similar to the interferon-stimulated response element. The protein encoded by this gene promotes or suppresses lineage-specific genes to regulate the differentation of lymphoid and myeloid lineage cells. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Interactions with Commensal and Pathogenic Bacteria Induce HIV-1 Latency in Macrophages through Altered Transcription Factor Recruitment to the LTR
Viglianti, Planelles, Hanley
J Virol (2021) 95 (7) DOI: 10.1128/JVI.02141-20
AI Summary: In this study, OriGene products including TRIF shRNA (OriGene, Cat# TL313386) and IRF8 shRNA (OriGene, Cat# TL313386B) were used to knock down gene expression and investigate the roles of TRIF and IRF8 in the repression of HIV-1 replication in macrophages.
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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