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Hoxa9 Mouse shRNA Plasmid (Locus ID 15405)

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SKU
TR500979
Hoxa9 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 15405
Synonyms D6a; D6a9; Hox-1.; Hox-1.7
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Hoxa9 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 15405). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC055059, NM_001277238, NM_010456, NM_010456.1, NM_010456.2, NM_010456.3, NM_001277238.1
UniProt ID P09631
Summary This gene is located in a cluster of developmentally and temporally regulated genes on chromosome 6 encoding proteins involved in pattern formation. These proteins contain a characteristic DNA-binding motif called a homeodomain and function in transcriptional regulation. There are four distinct clusters of similar genes on chromosomes 2, 6, 11, and 15. The protein encoded by this gene is important for hematopoeisis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

TWIST1-WDR5-Hottip regulates Hoxa9 chromatin to facilitate prostate cancer metastasis
Malek, Gajula, Williams et al
Cancer Res. (2017)
AI Summary: OriGene products, specifically shRNA constructs targeting mouse Hoxa9, human HOXA9, mouse Wdr5, and human WDR5, were used for gene knockdown experiments to investigate the roles of these genes in prostate cancer metastasis in this study.
Snippet: Page 7. 7 Retroviral experiments The shRNA constructs against mouse Hoxa9, human HOXA9, mouse Wdr5 and human WDR5 were used according to the manufacturer's instructions (OriGene). Cells were transduced with ... arrays were purchased from OriGene. on May ... All 2 versions Cite SaveSaving
The twist box domain is required for Twist1-induced prostate cancer metastasis
Gajula, Chettiar, Williams et al
Mol Cancer Res (2013) 11 (11), 1387-400 DOI: 10.1158/1541-7786.MCR-13-0218-T
AI Summary: In this study, OriGene products—including the Twist1 Myc-DDK-tagged expression plasmid (RC208727) and Twist1 shRNA (TL313981)—were used to manipulate Twist1 expression in prostate cancer cells, enabling the authors to investigate the role of the Twist box domain in promoting metastatic phenotypes.
FigureFigure
Showing 1-2 of 2 papers.
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