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Gnas Mouse shRNA Plasmid (Locus ID 14683)

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SKU
TR500832
Gnas - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 14683
Synonyms 5530400H20Rik; A930027G11Rik; C130027O20Rik; G; Ga; Galphas; Gn; Gnas1; Gnasxl; GPSA; Gs-; Gs-alpha; Gsa; GSP; N; Nes; Nesp; Nesp55; Nespl; Oed; Oed-Sml; Oedsml; P; P1; P2; P3; PHP1A; PHP1B; POH; SCG; SCG6; XL
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Gnas - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 14683). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001077507, NM_001077510, NM_010309, NM_010310, NM_019690, NM_022000, NM_201616, NM_201617, NM_201618, NR_003258, NM_022000.1, NM_022000.2, NM_022000.3, NM_010309.1, NM_010309.2, NM_010309.3, NM_010309.4, NM_001077507.1, NM_001077507.2, NM_201618.1, NM_201618.2, NM_201617.1, NM_201617.2, NM_001077510.1, NM_001077510.2, NM_001077510.3, NM_001077510.4, NM_201616.1, NM_201616.2, NM_019690.1, NM_019690.2, NM_019690.3, BC013824, BC013840, BC018408, BC034446, BC038067, BC048834, BC052228, BC061496, BC062654, BC080816, BC092055, BC106133, BM944582, NM_201616.3, NM_001077510.5
UniProt ID P63094
Summary This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, which is commonly found in imprinted genes and correlates with transcript expression. This gene has an antisense transcript. One of the transcripts produced from this locus, and the antisense transcript, are both paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Additional transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. provided by RefSeq, Jun 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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