Dsg3 Mouse shRNA Plasmid (Locus ID 13512)
Specifications
| Product Data | |
| Locus ID | 13512 |
|---|---|
| Synonyms | bal |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Dsg3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 13512). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC132058, BC132639, NM_030596, NM_030596.1, NM_030596.2, NM_030596.3, NM_030596.4 |
| UniProt ID | O35902 |
| Summary | This gene encodes a member of the cadherin family of proteins that forms an integral transmembrane component of desmosomes, the multiprotein complexes involved in cell adhesion, organization of the cytoskeleton, cell sorting and cell signaling. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Mice lacking the encoded protein exhibit loss of keratinocyte cell adhesion resulting in a phenotype that resembles that of patients with pemphigus vulgaris. This gene is located in a cluster of desmosomal cadherin genes on chromosome 18. provided by RefSeq, Feb 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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