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Cux1 Mouse shRNA Plasmid (Locus ID 13047)

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SKU
TR500463
Cux1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 13047
Synonyms CDP; Cutl1; Cux; Cux-1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components Cux1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 13047). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC090847, NM_001291233, NM_001291234, NM_001291238, NM_001291239, NM_001291240, NM_009986, NM_198602, NM_009986.1, NM_009986.2, NM_009986.3, NM_009986.4, NM_198602.1, NM_198602.2, NM_198602.3, NM_001291238.1, NM_001291239.1, NM_001291240.1, NM_001291234.1, NM_001291233.1, BC014289, BC054370, BC079570, BM944198
UniProt ID P53564
Summary Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III (PubMed:20510857). Also involved in the control of synaptogenesis (Probable). In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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