Ctsc Mouse shRNA Plasmid (Locus ID 13032)
Specifications
| Product Data | |
| Locus ID | 13032 |
|---|---|
| Synonyms | AI047818; CatC; D; DP; DPP1; DPPI |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Ctsc - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 13032). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC067063, NM_009982, NM_009982.1, NM_009982.2, NM_009982.3, NM_009982.4, NM_009982.5 |
| UniProt ID | P97821 |
| Summary | This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the dipeptidyl peptidase 1 light, heavy, and exclusion domain chains, which together comprise one subunit of the homotetrameric enzyme. This enzyme has amino dipeptidase activity and may play a role in the activation of granzymes during inflammation. Homozygous knockout mice for this gene exhibit impaired granzyme activation and enhanced survival in a sepsis model. provided by RefSeq, Aug 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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