Bmpr2 Mouse shRNA Plasmid (Locus ID 12168)
Specifications
| Product Data | |
| Locus ID | 12168 |
|---|---|
| Synonyms | 2610024H22Rik; AL117858; AW546137; BB189135; BM; BMP; BMP-; BMP-2; BMPR-2; BMPR-II; BMPRII; BRK-3; Gm20272 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Bmpr2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 12168). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_007561, NM_007561.1, NM_007561.2, NM_007561.3, NM_007561.4, BC148339, BC156868, BM940059 |
| UniProt ID | O35607 |
| Summary | This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. provided by RefSeq, Mar 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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