Bcl2l1 Mouse shRNA Plasmid (Locus ID 12048)
Specifications
| Product Data | |
| Locus ID | 12048 |
|---|---|
| Synonyms | Bcl; Bcl(X; Bcl(X)L; bcl-; bcl-x; Bcl-XL; bcl2-L-1; Bcl2l; BclX |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Bcl2l1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 12048). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC089016, BC089017, NM_001289716, NM_001289717, NM_001289739, NM_009743, NR_149254, NM_009743.1, NM_009743.2, NM_009743.3, NM_009743.4, NM_009743.5, NM_001289716.1, NM_001289717.1, NM_001289739.1 |
| UniProt ID | Q64373 |
| Summary | This gene encodes a member of the Bcl-2 family of apoptosis regulators. The encoded protein is localized to the inner and outer mitochondrial membranes and regulates the programmed cell death pathway during development and tissue homeostasis. This protein binds to voltage-dependent anion channels in the outer mitochondrial membrane to facilitate the uptake of calcium ions. Mice embryos lacking this gene survived for two weeks and exhibited cell death of immature hematopoietic cells and neurons. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. provided by RefSeq, Jan 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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