Prdx6 Mouse shRNA Plasmid (Locus ID 11758)
Specifications
| Product Data | |
| Locus ID | 11758 |
|---|---|
| Synonyms | 1-cys; 1-Cys Prx; 1-cysPrx; 9430088D19Rik; a; AA690119; aiPLA2; Aop2; Brp-; Brp-12; CP-; CP-3; GP; GPx; LPCAT-5; Ltw; Ltw-; Ltw-4; Ltw4; Lvtw; Lvtw-4; N; NSGPx; ORF06; Prdx5 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Prdx6 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 11758). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC013489, BC061181, NM_001303408, NM_007453, NR_130150, NM_007453.1, NM_007453.2, NM_007453.3, NM_007453.4, NM_001303408.1 |
| UniProt ID | O08709 |
| Summary | This gene encodes a member of the peroxiredoxin family of peroxidases. The encoded protein is a bifunctional enzyme that has glutathione peroxidase and phospholipase activities. This protein is an antioxidant that reduces peroxidized membrane phospholipids and plays an important role in phospholipid homeostasis based on its ability to generate lysophospholipid substrate for the remodeling pathway of phospholipid synthesis. Mice lacking this gene are sensitive to oxidant stress, have altered lung phospholipid metabolism and susceptible to skin tumorigenesis. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 4. provided by RefSeq, Dec 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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