Alox8 Mouse shRNA Plasmid (Locus ID 11688)
Specifications
| Product Data | |
| Locus ID | 11688 |
|---|---|
| Synonyms | 8-L; 8-LOX; 8S-; 8S-LOX; 15-LOX-2; 15-LOX-B; Alox; Alox15b |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | Alox8 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 11688). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC015253, NM_009661, NM_009661.1, NM_009661.2, NM_009661.3, NM_009661.4 |
| UniProt ID | O35936 |
| Summary | This gene belongs to the lipoxygenase (LOX) gene family whose members encode enzymes that catalyze the addition of molecular oxygen to polyunsaturated fatty acids (PUFAs) to yield fatty acid hydroperoxides. The encoded enzyme preferentially metabolizes arachidonic acid to yield 8-hydroxyeicosatetraenoic acid (8-HETE), while metabolizing linoleic acid less efficiently. The gene may also function as a tumor suppressor. This gene is located in a cluster of related genes that spans approximately 75 kilobases on chromosome 11. provided by RefSeq, Jan 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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