OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

TRPM7 Human shRNA Plasmid Kit (Locus ID 54822)

Be the first to review this product
SKU
TR320704
TRPM7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

Frequently Bought Together (2)

TA328749 Rabbit Polyclonal Anti-TRPM7
50 ul
$1,145.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "TRPM7 or NM_001301212"

Specifications
Specifications
Product Data
Locus ID 54822
Synonyms ALSPDC; CHAK; CHAK1; LTrpC-7; LTRPC7; TRP-PLIK
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components TRPM7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 54822). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001301212, NM_017672, NR_149152, NR_149153, NR_149154, NM_017672.1, NM_017672.2, NM_017672.3, NM_017672.4, NM_017672.5, NM_001301212.1, BC028843, BC051024, BC128987, BC128988, BC169233, BC169234, BC169235, NM_001301212.2, NM_017672.6
UniProt ID Q96QT4
Summary This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Magnesium-Induced Cell Survival Is Dependent on TRPM7 Expression and Function
Sun, Sukumaran, Singh
Mol. Neurobiol. (2019) 57 (1), 528-538 DOI: 10.1007/s12035-019-01713-7
AI Summary: OriGene's shRNA plasmid targeting human TRPM7 was used in this study to transiently reduce TRPM7 expression, enabling the authors to investigate the channel's role in magnesium homeostasis and cell survival in dopaminergic cells.
Snippet: individual experiments. For transient transfection experiments, shRNA plasmid that targets the coding sequence of human TRPM7 was obtained from Origene (Rockville, MD) and transfected using lipofectamine. Similarly, for
Cholesterol-induced activation of TRPM7 regulate cell proliferation, migration, and viability of human prostate cells
Sun, Sukumaran, Varma et al
Biochim. Biophys. Acta (2014)
Cited by 90
AI Summary: OriGene products, specifically the human TRPM7 shRNA plasmid and TRPM7 cDNA construct, were used for gene silencing and overexpression experiments to investigate the role of TRPM7 in cholesterol-induced proliferation, migration, and viability of human prostate cells.
Snippet: until reaching 90% confluence. For transfection experiments shRNA plasmid that targets the coding sequence of human TRPM7 were obtained from Origene and TRPM7cDNA construct was used. Cells were transfected with ... Cite SaveSaving
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products