BRD4 Human shRNA Plasmid Kit (Locus ID 23476)

SKU TR320670

BRD4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 23476
• Synonyms: CAP; HUNK1; HUNKI; MCAP
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: BRD4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23476). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001330384, NM_014299, NM_058243, NM_014299.1, NM_014299.2, NM_058243.1, NM_058243.2, BC000156, BC008354, BC030158, BC035266, BC038988, BC047888, BC067129, BC091649, NM_058243.3
• UniProt ID: O60885
• Summary: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient