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RET Human shRNA Plasmid Kit (Locus ID 5979)

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SKU
TR320512
RET - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 5979
Synonyms PTC, MTC1, HSCR1, MEN2A, MEN2B, RET51
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components RET - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5979). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_000323, NM_020629, NM_020630, NM_020975, NM_001355216, NM_020630.1, NM_020630.2, NM_020630.3, NM_020630.4, NM_020975.2, NM_020975.3, NM_020975.4, NM_000323.2, BC004257, BC004257.1, BC003072, BM661773, BM703293, NM_020975.6
UniProt ID P07949
Summary This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. provided by RefSeq, Sep 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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