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JNK3 (MAPK10) Human shRNA Plasmid Kit (Locus ID 5602)

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SKU
TR320487
MAPK10 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 5602
Synonyms JNK3; JNK3A; p54bSAPK; p493F12; PRKM10; SAPK1b
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components MAPK10 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5602). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001318067, NM_001318068, NM_001318069, NM_002753, NM_138980, NM_138981, NM_138982, NM_001351624, NM_001351625, NM_002753.1, NM_002753.2, NM_002753.3, NM_002753.4, NM_138980.1, NM_138980.2, NM_138980.3, NM_138982.1, NM_138982.2, NM_138982.3, NM_138981.1, NM_138981.2, BC035057, BC035057.1, BC065516, BC065516.1, BC022492, BC051731, NM_001363657, NM_138982.4, NM_002753.5, NM_138980.4
UniProt ID P53779
Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. provided by RefSeq, Dec 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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