PPAR alpha (PPARA) Human shRNA Plasmid Kit (Locus ID 5465)

SKU TR320458

PPARA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 5465
• Synonyms: hPPAR; NR1C1; PPAR; PPAR-alpha; PPARalpha
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: PPARA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5465). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: BC000052, NM_001001928, NM_001001929, NM_001001930, NM_005036, NM_032644, NM_005036.1, NM_005036.2, NM_005036.3, NM_005036.4, NM_001001928.1, NM_001001928.2, NM_001001929.2, NM_001001930.2, NM_032644.3, BC004162, BC009069, BC071932, NM_001362872, NM_001362873, NM_005036.6, NM_001001928.3
• UniProt ID: Q07869
• Summary: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient