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DDR2 Human shRNA Plasmid Kit (Locus ID 4921)

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SKU
TR320440
DDR2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "DDR2 or NM_001014796"

Specifications
Specifications
Product Data
Locus ID 4921
Synonyms MIG20a; NTRKR3; TKT; TYRO10; WRCN
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components DDR2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4921). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001014796, NM_006182, NM_001354982, NM_001354983, NM_001014796.1, NM_006182.1, NM_006182.2, BC052998, BC052998.2, NM_001014796.3, NM_006182.4
UniProt ID Q16832
Summary This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1
Xie, Lin, Ye et al
J. Exp. Clin. Cancer Res. (2015) 34 (1), 101 DOI: 10.1186/s13046-015-0218-6
Cited by 101
AI Summary: OriGene products contributed to this study by providing the DDR2 expressing plasmid (pCMV6-XL6), DDR2 shRNA, and scrambled shRNA vector (pRS), which were used to manipulate DDR2 expression and investigate its role in hepatocellular carcinoma cell invasion and signaling pathways.
Snippet: Expressing plasmids and RNAi transfection. The DDR2 expressing plasmid and its empty plasmid pCMV6-XL6 were both obtained from Origene Technologies Inc. ... The DDR2 shRNA and scrambled shRNA vector pRS were also purchased from Origene Technologies ... Cite SaveSaving
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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