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BMPR1B Human shRNA Plasmid Kit (Locus ID 658)

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SKU
TR320273
BMPR1B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 658
Synonyms ALK-6; ALK6; AMDD; BDA1D; BDA2; CDw293
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components BMPR1B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 658). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001203, NM_001256792, NM_001256793, NM_001256794, NM_001203.1, NM_001203.2, NM_001256792.1, NM_001256794.1, NM_001256793.1, BC069796, BC069796.1, BC047773, BC069803, NM_001203.3, NM_001256793.2
UniProt ID O00238
Summary This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Feb 2012
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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