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ID4 Human shRNA Plasmid Kit (Locus ID 3400)

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SKU
TR319484
ID4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 3400
Synonyms bHLHb27; IDB4
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ID4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3400). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001546, NM_001546.1, NM_001546.2, NM_001546.3, BC014941, BC014941.1, NM_001546.4
UniProt ID P47928
Summary This gene encodes a member of the inhibitor of DNA binding (ID) protein family. The encoded protein lacks DNA binding ability, and instead regulates gene expression through binding to and inhibiting basic helix-loop-helix transcription factors. This protein has been implicated in the regulation of diverse cellular processes that play a role in development and tumorigenesis. provided by RefSeq, Aug 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Induction of lumen formation in a 3D model of mammary morphogenesis by transcriptional regulator ID4: Role of CaMK2D in the epigenetic regulation of ID4 gene expression
Nguyen, Shively
J. Biol. Chem. (2016)
AI Summary: OriGene's pCMV6 plasmids for CaMK2D and ID4 were used to manipulate the expression of these genes in MCF7 cells, enabling the study of their roles in lumen formation and epigenetic regulation in breast cancer models.
Snippet: 5-aza-2'-deoxycytidine (DAC) and trichostatin A (TSA) were from Sigma- Aldrich (St. Louis, MO). CaMKII-specific inhibitor KN-93 and inactive analog KN-92 were from Calbiochem. pCMV6 plasmids for CaMK2D and ID4 were from OriGene Technologies, Inc (Rockville ... Cite SaveSaving
Inhibitor of DNA binding-4 promotes angiogenesis and growth of glioblastoma multiforme by elevating matrix GLA levels
Kuzontkoski, Mulligan-Kehoe, Harris et al
Oncogene (2010) 29 (26), 3793-802 DOI: 10.1038/onc.2010.147
Cited by 57
AI Summary: OriGene products, specifically the ID4 (RC209307) and MGP (RC223682) expression plasmids, were used to manipulate gene expression in glioblastoma cell cultures, enabling the authors to investigate the roles of ID4 and MGP in promoting tumor angiogenesis and growth.
Showing 1-2 of 2 papers.
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