LTC4S Human shRNA Plasmid Kit (Locus ID 4056)
SKU
TR319192
LTC4S - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 4056 |
|---|---|
| Synonyms | leukotriene C4 synthase; MGC33147 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | LTC4S - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4056). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000897, NM_145867, NM_145867.1, BC029498, BC029498.1 |
| UniProt ID | Q16873 |
| Summary | The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages
Dalli, Vlasakov, Riley et al
PNAS (2016) 113 (43), 12232-12237 DOI: 10.1073/pnas.1607003113
Dalli, Vlasakov, Riley et al
PNAS (2016) 113 (43), 12232-12237 DOI: 10.1073/pnas.1607003113
AI Summary: OriGene’s human recombinant LTC4S (HrLTC4S) enzyme was used to investigate the biosynthetic conversion of maresin epoxide intermediates to MCTR1 in human macrophages, helping to elucidate key steps in the tissue regeneration pathway.
Snippet: HrLTC4S (40 ng/20 μL;Origene) and hrGSTM4 (61 ng/20 μL;Creative Biomart) were suspended in 25 mM Tris·HCl containing 5 mM reduced glutathione and 0.05% Triton X-100 (pH 7.8) and incubated with 13S, 14S-eMaR or LTA4 (0.3, 1, 3, 10, 30, and 100 μM) at room temperature for 2 min. The incubations were quenched using 2 volumes of MeOH and were profiled using lipid mediator metabololipidomics
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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