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MIF Human shRNA Plasmid Kit (Locus ID 4282)

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SKU
TR319111
MIF - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 4282
Synonyms GIF; GLIF; MMIF
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components MIF - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4282). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_002415, NM_002415.1, BC022414, BC022414.1, BC000447, BC007376, BC007676, BC008914, BC013976, BC051440, BC053376, NM_002415.2
UniProt ID P14174
Summary This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

UHRF1 regulates the transcriptional repressor HBP1 through MIF in T acute lymphoblastic leukemia
Yao, Luo, Zeng et al
Oncol Rep (2021) 46 (1) DOI: 10.3892/or.2021.8082
Cited by 40
AI Summary: OriGene products, including shRNA plasmids for UHRF1 (GI333964), HBP1 (TL312507), MIF (TR319111), a control shRNA (TR30007), an HBP1 overexpression plasmid (RG202260), and a control plasmid (PS100010), were used to manipulate gene expression in leukemia cells, enabling the study of UHRF1, HBP1, and MIF roles in T acute lymphoblastic leukemia.
Snippet: The shRNA plas‑ mids included UHRF1 (GI333964), HBP1 (TL312507), MIF (TR319111), or control (TR30007). The overexpression plasmid was HBP1 (RG202260) or control (PS100010) (Origene). In vivo leukemia cell transplantation
Macrophage Migration Inhibitory Factor Regulates Akt Signaling in Hypoxic Culture to Modulate Senescence of Human Mesenchymal Stem Cells
Palumbo, Tsai, Li
Stem Cells Dev. (2013)
Cited by 49
AI Summary: OriGene products contributed to this study by providing the pCMV6-Entry vector containing the MIF gene for overexpression and the HuSH pGFP-V-RS control shRNA plasmid, which were used to manipulate MIF expression and investigate its role in regulating Akt signaling and senescence in human mesenchymal stem cells.
Snippet: To construct a plasmid for MIF overexpression, referred to as MIFover, the coding sequence of MIF gene of the pCMV6-Entry vector (Origene, Rockville, MD) was isolated by ... HuSH pGFP-V-RS (Origene). The control shRNA plasmid containing a non-specific scrambled ... Cite SaveSaving
Showing 1-2 of 2 papers.
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