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alpha Synuclein (SNCA) Human shRNA Plasmid Kit (Locus ID 6622)

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SKU
TR318860
SNCA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 6622
Synonyms NACP; PARK1; PARK4; PD1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components SNCA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 6622). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_000345, NM_001146054, NM_001146055, NM_007308, NM_000345.1, NM_000345.2, NM_000345.3, NM_007308.1, NM_007308.2, NM_001146054.1, NM_001146055.1, BC108275, BC013293, NM_001146054.2, NM_001146055.2, NM_000345.4
UniProt ID P37840
Summary Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. provided by RefSeq, Feb 2016
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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