ZDHHC19 Human shRNA Plasmid Kit (Locus ID 131540)
Specifications
| Product Data | |
| Locus ID | 131540 |
|---|---|
| Synonyms | DHHC19 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ZDHHC19 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 131540). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001039617, NM_144637, NR_135617, NR_135618, NM_001039617.1, BC022078, BC034801, NM_001039617.2 |
| UniProt ID | Q8WVZ1 |
| Summary | Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS (PubMed:31462771, PubMed:20074548). Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer (PubMed:31462771). Palmitoylation of RRAS is linked to cell viability (PubMed:20074548). May be involved in S-stearoylation of STAT3 (Probable).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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