NIRF (UHRF2) Human shRNA Plasmid Kit (Locus ID 115426)
Specifications
| Product Data | |
| Locus ID | 115426 |
|---|---|
| Synonyms | NIRF, URF2, RNF107, MGC33463, DKFZp434B0920, DKFZp686G0837, RP11-472F14.2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | UHRF2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 115426). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_152306, NM_152896, NR_046386, NM_152896.1, NM_152896.2, BC028397, NM_152896.3 |
| UniProt ID | Q96PU4 |
| Summary | This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. provided by RefSeq, Feb 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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