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COL23A1 Human shRNA Plasmid Kit (Locus ID 91522)

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SKU
TR317712
COL23A1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 91522
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components COL23A1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 91522). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_173465, NM_173465.1, NM_173465.2, NM_173465.3, BC042428, NM_173465.4
UniProt ID Q86Y22
Summary COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 PubMed 12644459).supplied by OMIM, Mar 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

A role for collagen XXIII in cancer cell adhesion, anchorage-independence and metastasis
Spivey, Chung, Banyard et al
Oncogene (2012) 31 (18), 2362-72 DOI: 10.1038/onc.2011.406
Cited by 42
AI Summary: OriGene’s pRS shRNA plasmids (TR317712) were used to knock down collagen XXIII in cancer cell lines, enabling the study of collagen XXIII’s role in cell adhesion, anchorage-independence, and metastasis.
Snippet: For knockdown studies, H460 or H1299 cells were transfected with an empty pRS vector, pRS encoding shRNA against collagen XXIII (sh#57 or sh#58) or pRS encoding ineffective shRNA against GFP (shGFP) (TR317712, Origene, Rockville, MD, USA) using Lipofectamine
Collagen XXIII: a potential biomarker for the detection of primary and recurrent non-small cell lung cancer
Spivey, Banyard, Solis et al
Cancer Epidemiol Biomarkers Prev (2010) 19 (5), 1362-72 DOI: 10.1158/1055-9965.EPI-09-1095
AI Summary: OriGene products contributed to this study by providing the anti-collagen XXIII antibody (catalog #TA500439), which was used for immunohistochemical staining and Western blot analysis to detect collagen XXIII expression in tissue and urine samples.
FigureFigure
Showing 1-2 of 2 papers.
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