CD177 Human shRNA Plasmid Kit (Locus ID 57126)
Specifications
| Product Data | |
| Locus ID | 57126 |
|---|---|
| Synonyms | HNA-2a; HNA2A; NB1; NB1 GP; PRV-1; PRV1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CD177 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 57126). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_020406, NM_020406.1, NM_020406.2, NM_020406.3, BC029167, BC029167.1, NM_020406.4 |
| UniProt ID | Q8N6Q3 |
| Summary | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. provided by RefSeq, Apr 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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