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VENTX Human shRNA Plasmid Kit (Locus ID 27287)

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SKU
TR317112
VENTX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 27287
Synonyms HPX42B; NA88A; VENTX2
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components VENTX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 27287). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_014468, NM_014468.1, NM_014468.2, NM_014468.3, BC108915, BC108916, NM_014468.4
UniProt ID O95231
Summary This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

VentX, a novel lymphoid-enhancing factor/T-cell factor-associated transcription repressor, is a putative tumor suppressor
Gao, Le, Wu et al
Cancer Res (2010) 70 (1), 202-11 DOI: 10.1158/0008-5472.CAN-09-2668
AI Summary: In this paper, OriGene products—specifically the VentX cDNA clone and anti-VentX antibody—were used to study the expression and functional role of VentX as a putative tumor suppressor and negative regulator of Wnt/beta-catenin signaling in hematopoietic cells.
Showing 1-1 of 1 papers.
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