PTPN7 Human shRNA Plasmid Kit (Locus ID 5778)
Specifications
| Product Data | |
| Locus ID | 5778 |
|---|---|
| Synonyms | BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PTPN7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5778). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001199797, NM_002832, NM_080588, NM_080589, NR_037663, NR_037664, NM_002832.1, NM_002832.2, NM_002832.3, NM_080588.1, NM_080588.2, NM_001199797.1, NM_080589.1, BC001746, BC001746.1, NM_001364877, NM_001364878, NM_001199797.2 |
| UniProt ID | P35236 |
| Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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