PTPN7 Human shRNA Plasmid Kit (Locus ID 5778)

SKU
TR316685
PTPN7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 5778
Synonyms BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PTPN7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5778). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001199797, NM_002832, NM_080588, NM_080589, NR_037663, NR_037664, NM_002832.1, NM_002832.2, NM_002832.3, NM_080588.1, NM_080588.2, NM_001199797.1, NM_080589.1, BC001746, BC001746.1, NM_001364877, NM_001364878, NM_001199797.2
UniProt ID P35236
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Dec 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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