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EYA3 Human shRNA Plasmid Kit (Locus ID 2140)

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SKU
TR316534
EYA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Other products for "EYA3 or NM_001282560"

Specifications
Specifications
Product Data
Locus ID 2140
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components EYA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2140). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001282560, NM_001282561, NM_001282562, NM_001990, NM_172098, NR_104214, NM_001990.1, NM_001990.2, NM_001990.3, NM_001282562.1, NM_001282561.1, NM_001282560.1, NM_172098.1, BC029500, BC041667, NM_001282560.2, NM_001990.4
UniProt ID Q99504
Summary This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Sep 2013
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

Regulation of the innate immune response by threonine-phosphatase of Eyes absent
Okabe, Sano, Nagata
Nature (2009) 460 (7254), 520-4 DOI: 10.1038/nature08138
Cited by 167
AI Summary: OriGene products, specifically the EYA4 expression plasmid (OriGene, MC205779) and EYA4 shRNA (OriGene, TG313747), were used in this study to manipulate EYA4 levels in cells, enabling the authors to investigate the role of EYA4 in regulating the innate immune response to undigested DNA and viral infection.
Showing 1-1 of 1 papers.
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